{"id":15,"date":"2025-09-20T13:18:03","date_gmt":"2025-09-20T13:18:03","guid":{"rendered":"https:\/\/matigenthailand.com\/?page_id=15"},"modified":"2025-09-25T06:27:06","modified_gmt":"2025-09-25T06:27:06","slug":"usage-guidance","status":"publish","type":"page","link":"https:\/\/matigenthailand.com\/en\/usage-guidance\/","title":{"rendered":"Usage & Comparison"},"content":{"rendered":"
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Instructions for Use & Product Comparison<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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Purposes uses instructions for use product comparison and other information<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Purposes and Usages<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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  • \n\t\t\t\t\t\t\t\t\t\tFor surgical operations on weak body tissues, damaged areas, and membrane rupture.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
  • \n\t\t\t\t\t\t\t\t\t\tOther purposes include burns, trauma, skin defects and reconstruction of plastic surgery without side effect.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Preparation Before Use<\/h2>\t\t\t\t<\/div>\n\t\t
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    Check for any defects and do not use if package is open or damaged.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Check the shelf life and read the instructions carefully before use.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    The product is double packed in packaging sterilized and must be used or handled under aseptic conditions.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Do not use sharp instruments or jagged tweezers when handling the product.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    How to Use & Order of Use<\/h2>\t\t\t\t<\/div>\n\t\t
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    This product must be used by a medical specialist, with sterilized gloves and surgical equipment.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Open the sterilized double packages and take out the product.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Soak in sterile saline solution for at least one minute before use and\/or keep in sterile saline solution to prevent from drying.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Check the area where grafting or replacement is needed and cut out the product in the right shape for grafting.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    This product can be overlapped or stacked in layers to fit the area, as the case may require. (stack by cutting instead of folding.)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Suture after applying the product.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Handling After Use<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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    • \n\t\t\t\t\t\t\t\t\t\tThe leftover should be discarded and should not be re-used.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
    • \n\t\t\t\t\t\t\t\t\t\tDiscarded properly as an infected or a medical garbage.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      Precautions <\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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      • \n\t\t\t\t\t\t\t\t\t\tThis product must be used by a medical specialist.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
      • \n\t\t\t\t\t\t\t\t\t\tDo no t use on infected areas with redness, abscess, warmth, and edema.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
      • \n\t\t\t\t\t\t\t\t\t\tRemove the product immediately in case of rash, burning sensation, allergic reaction or symptoms of infection.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
      • \n\t\t\t\t\t\t\t\t\t\tUse the product immediately after opening. Any remaining part after use shall be discarded.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
      • \n\t\t\t\t\t\t\t\t\t\tThis product cannot be reused.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
      • \n\t\t\t\t\t\t\t\t\t\tProduct safety is not guaranteed for pregnant women. Please consult a medical specialist before use.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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        Restrictions <\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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        Do not use on the following patients:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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        • \n\t\t\t\t\t\t\t\t\t\tPatients sensitive to pig-derived collagen products<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
        • \n\t\t\t\t\t\t\t\t\t\tPatients with auto-immune disease and diosmosis such as lupus or dermatomyositis.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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          Storage Conditions\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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          • Keep tightly sealed at room temperature (1-30 \u00b0C)<\/li>
          • Avoid direct sunlight, high temperature and humidity<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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            Shelf Life\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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            • Check the product packaging or labeling for the expiration date.<\/li>
            • Do not use if the product is expired.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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              Competitive Analysis & Comparison<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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              \u0e40\u0e25\u0e37\u0e48\u0e2d\u0e19\u0e15\u0e32\u0e23\u0e32\u0e07\u0e0b\u0e49\u0e32\u0e22 \u0e02\u0e27\u0e32 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e14\u0e39\u0e02\u0e49\u0e2d\u0e21\u0e39\u0e25\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e40\u0e15\u0e34\u0e21<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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              Aspect<\/th>Matigen\u00ae<\/th>hADM (from human skin)<\/th>pADM (from porcine skin)<\/th>\n<\/tr>\n<\/thead>\n
              Biocompatibility<\/td>High biocompatibility with preserved extracellular matrix; designed to minimize immune response<\/td>Very high, closely resembles human tissue<\/td>Good, but slightly lower than human<\/td>\n<\/tr>\n
              Immune Risk<\/td>Very low; processed to remove cells, fats, viruses, and endotoxins.<\/td>Low (allograft)<\/td>Slightly higher (xenograft), but reduced with decellularization<\/td>\n<\/tr>\n
              Neovascularization \/ Integration<\/td>Rapid engraftment and stable integration; slower degradation than other ADMs<\/td>Excellent, new tissue integrates quickly<\/td>Good, though some studies report slower integration<\/td>\n<\/tr>\n
              Mechanical Strength<\/td>Available in multiple thicknesses (3\u20134 mm), maintains durability in collagenase test<\/td>Moderate to high, depending on model\/thickness<\/td>Often slightly stronger, suitable for oral\/nasal augmentation<\/td>\n<\/tr>\n
              Source \/ Sustainability<\/td>Manufactured from porcine dermis with standardized processing
              \n<\/td>              		Limited (requires human donation)<\/td>Abundant, easily reproducible<\/td>\n<\/tr>\n
              Cost<\/td>Moderately priced; generally lower than hADM but higher than basic pADM<\/td>Higher (due to scarcity and higher processing cost)<\/td>Lower \/ more accessible\nRetail price \uf0bb 600 \u2013 800 THB\/Unit<\/td>\n<\/tr>\n
              Patient Acceptance<\/td>Accepted in most regions; some cultural\/religious restrictions due to porcine origin<\/td>Some patients may have ethical concerns about human use<\/td>Some patients (especially Muslim\/Jewish) may refuse due to porcine origin<\/td>\n<\/tr>\n
              Typical Applications<\/td>Rhinoplasty (tip\/saddle support), reconstructive surgery, soft-tissue augmentation<\/td>Breast reconstruction, burn surgery, rhinoplasty<\/td>Periodontal graft, dental implant soft-tissue augmentation<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

              \u0e04\u0e33\u0e41\u0e19\u0e30\u0e19\u0e33\u0e01\u0e32\u0e23\u0e43\u0e0a\u0e49\u0e07\u0e32\u0e19\u0e41\u0e25\u0e30\u0e40\u0e1b\u0e23\u0e35\u0e22\u0e1a\u0e40\u0e17\u0e35\u0e22\u0e1a\u0e2a\u0e34\u0e19\u0e04\u0e49\u0e32\u0e25\u0e31\u0e01\u0e29\u0e13\u0e30\u0e40\u0e14\u0e35\u0e22\u0e27\u0e01\u0e31\u0e19 \u0e27\u0e31\u0e15\u0e16\u0e38\u0e1b\u0e23\u0e30\u0e2a\u0e07\u0e04\u0e4c \u0e02\u0e49\u0e2d\u0e1a\u0e48\u0e07\u0e43\u0e0a\u0e49 \u0e27\u0e34\u0e18\u0e35\u0e43\u0e0a\u0e49\u0e07\u0e32\u0e19 \u0e01\u0e32\u0e23\u0e40\u0e1b\u0e23\u0e35\u0e22\u0e19\u0e1a\u0e40\u0e17\u0e35\u0e22\u0e1a\u0e2a\u0e34\u0e19\u0e04\u0e49\u0e32 \u0e41\u0e25\u0e30\u0e2d\u0e37\u0e48\u0e19\u0e46 \u0e27\u0e31\u0e15\u0e16\u0e38\u0e1b\u0e23\u0e30\u0e2a\u0e07\u0e04\u0e4c\u0e41\u0e25\u0e30\u0e02\u0e49\u0e2d\u0e1a\u0e48\u0e07\u0e43\u0e0a\u0e49 \u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e1c\u0e48\u0e32\u0e15\u0e31\u0e14\u0e1a\u0e19\u0e40\u0e19\u0e37\u0e49\u0e2d\u0e40\u0e22\u0e37\u0e48\u0e2d\u0e17\u0e35\u0e48\u0e2d\u0e48\u0e2d\u0e19\u0e41\u0e2d \u0e1a\u0e23\u0e34\u0e40\u0e27\u0e13\u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e04\u0e27\u0e32\u0e21\u0e40\u0e2a\u0e35\u0e22\u0e2b\u0e32\u0e22 \u0e41\u0e25\u0e30\u0e20\u0e32\u0e27\u0e30\u0e01\u0e32\u0e23\u0e09\u0e35\u0e01\u0e02\u0e32\u0e14\u0e02\u0e2d\u0e07\u0e40\u0e19\u0e37\u0e49\u0e2d\u0e40\u0e22\u0e37\u0e48\u0e2d (membrane rupture) \u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e41\u0e1c\u0e25\u0e44\u0e1f\u0e44\u0e2b\u0e21\u0e49 (burns) \u0e01\u0e32\u0e23\u0e1a\u0e32\u0e14\u0e40\u0e08\u0e47\u0e1a (trauma) \u0e04\u0e27\u0e32\u0e21\u0e1a\u0e01\u0e1e\u0e23\u0e48\u0e2d\u0e07\u0e02\u0e2d\u0e07\u0e1c\u0e34\u0e27\u0e2b\u0e19\u0e31\u0e07 (skin defects) \u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e17\u0e33\u0e28\u0e31\u0e25\u0e22\u0e01\u0e23\u0e23\u0e21\u0e42\u0e04\u0e23\u0e07\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e43\u0e2b\u0e21\u0e48 (reconstruction in plastic surgery) \u0e42\u0e14\u0e22\u0e44\u0e21\u0e48\u0e01\u0e48\u0e2d\u0e43\u0e2b\u0e49\u0e40\u0e01\u0e34\u0e14\u0e1c\u0e25\u0e02\u0e49\u0e32\u0e07\u0e40\u0e04\u0e35\u0e22\u0e07 (side effects) \u0e01\u0e32\u0e23\u0e40\u0e15\u0e23\u0e35\u0e22\u0e21\u0e01\u0e48\u0e2d\u0e19\u0e43\u0e0a\u0e49\u0e07\u0e32\u0e19 \u0e15\u0e23\u0e27\u0e08\u0e2a\u0e2d\u0e1a\u0e04\u0e27\u0e32\u0e21\u0e0a\u0e33\u0e23\u0e38\u0e14 \u0e41\u0e25\u0e30\u0e2d\u0e22\u0e48\u0e32\u0e43\u0e0a\u0e49\u0e2b\u0e32\u0e01\u0e1a\u0e23\u0e23\u0e08\u0e38\u0e20\u0e31\u0e13\u0e11\u0e4c\u0e16\u0e39\u0e01\u0e40\u0e1b\u0e34\u0e14\u0e2b\u0e23\u0e37\u0e2d\u0e40\u0e2a\u0e35\u0e22\u0e2b\u0e32\u0e22 \u0e15\u0e23\u0e27\u0e08\u0e2a\u0e2d\u0e1a shelf life \u0e41\u0e25\u0e30\u0e2d\u0e48\u0e32\u0e19\u0e04\u0e33\u0e41\u0e19\u0e30\u0e19\u0e33\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e25\u0e30\u0e40\u0e2d\u0e35\u0e22\u0e14\u0e01\u0e48\u0e2d\u0e19\u0e43\u0e0a\u0e49 \u0e1c\u0e25\u0e34\u0e15\u0e20\u0e31\u0e13\u0e11\u0e4c\u0e19\u0e35\u0e49\u0e1a\u0e23\u0e23\u0e08\u0e38\u0e2a\u0e2d\u0e07\u0e0a\u0e31\u0e49\u0e19\u0e43\u0e19\u0e1a\u0e23\u0e23\u0e08\u0e38\u0e20\u0e31\u0e13\u0e11\u0e4c\u0e17\u0e35\u0e48 sterilized \u0e41\u0e25\u0e30\u0e15\u0e49\u0e2d\u0e07\u0e43\u0e0a\u0e49\u0e2b\u0e23\u0e37\u0e2d\u0e08\u0e31\u0e14\u0e01\u0e32\u0e23\u0e20\u0e32\u0e22\u0e43\u0e15\u0e49\u0e2a\u0e20\u0e32\u0e27\u0e30 aseptic \u0e2b\u0e49\u0e32\u0e21\u0e43\u0e0a\u0e49\u0e40\u0e04\u0e23\u0e37\u0e48\u0e2d\u0e07\u0e21\u0e37\u0e2d\u0e04\u0e21\u0e2b\u0e23\u0e37\u0e2d\u0e41\u0e2b\u0e19\u0e1a\u0e1b\u0e25\u0e32\u0e22\u0e2b\u0e22\u0e31\u0e01\/\u0e1a\u0e34\u0e48\u0e19\u0e43\u0e19\u0e01\u0e32\u0e23\u0e08\u0e31\u0e14\u0e01\u0e32\u0e23\u0e1c\u0e25\u0e34\u0e15\u0e20\u0e31\u0e13\u0e11\u0e4c \u0e27\u0e34\u0e18\u0e35\u0e43\u0e0a\u0e49\u0e41\u0e25\u0e30\u0e25\u0e33\u0e14\u0e31\u0e1a\u0e02\u0e31\u0e49\u0e19\u0e15\u0e2d\u0e19\u0e01\u0e32\u0e23\u0e43\u0e0a\u0e49 \u0e1c\u0e25\u0e34\u0e15\u0e20\u0e31\u0e13\u0e11\u0e4c\u0e19\u0e35\u0e49\u0e15\u0e49\u0e2d\u0e07\u0e43\u0e0a\u0e49\u0e42\u0e14\u0e22\u0e41\u0e1e\u0e17\u0e22\u0e4c\u0e1c\u0e39\u0e49\u0e40\u0e0a\u0e35\u0e48\u0e22\u0e27\u0e0a\u0e32\u0e0d \u0e1e\u0e23\u0e49\u0e2d\u0e21\u0e16\u0e38\u0e07\u0e21\u0e37\u0e2d\u0e17\u0e35\u0e48 sterilized \u0e41\u0e25\u0e30 surgical equipment \u0e40\u0e1b\u0e34\u0e14\u0e1a\u0e23\u0e23\u0e08\u0e38\u0e20\u0e31\u0e13\u0e11\u0e4c\u0e41\u0e1a\u0e1a double \u0e17\u0e35\u0e48 sterilized \u0e41\u0e25\u0e49\u0e27 \u0e41\u0e25\u0e30\u0e19\u0e33\u0e1c\u0e25\u0e34\u0e15\u0e20\u0e31\u0e13\u0e11\u0e4c\u0e2d\u0e2d\u0e01 \u0e41\u0e0a\u0e48\u0e43\u0e19 sterile 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