Instructions for Use & Product Comparison
Purposes uses instructions for use product comparison and other information
Purposes and Usages
- For surgical operations on weak body tissues, damaged areas, and membrane rupture.
- Other purposes include burns, trauma, skin defects and reconstruction of plastic surgery without side effect.
Preparation Before Use
Check for any defects and do not use if package is open or damaged.
Check the shelf life and read the instructions carefully before use.
The product is double packed in packaging sterilized and must be used or handled under aseptic conditions.
Do not use sharp instruments or jagged tweezers when handling the product.
How to Use & Order of Use
This product must be used by a medical specialist, with sterilized gloves and surgical equipment.
Open the sterilized double packages and take out the product.
Soak in sterile saline solution for at least one minute before use and/or keep in sterile saline solution to prevent from drying.
Check the area where grafting or replacement is needed and cut out the product in the right shape for grafting.
This product can be overlapped or stacked in layers to fit the area, as the case may require. (stack by cutting instead of folding.)
Suture after applying the product.
Handling After Use
- The leftover should be discarded and should not be re-used.
- Discarded properly as an infected or a medical garbage.
Precautions
- This product must be used by a medical specialist.
- Do no t use on infected areas with redness, abscess, warmth, and edema.
- Remove the product immediately in case of rash, burning sensation, allergic reaction or symptoms of infection.
- Use the product immediately after opening. Any remaining part after use shall be discarded.
- This product cannot be reused.
- Product safety is not guaranteed for pregnant women. Please consult a medical specialist before use.
Restrictions
Do not use on the following patients:
- Patients sensitive to pig-derived collagen products
- Patients with auto-immune disease and diosmosis such as lupus or dermatomyositis.
Storage Conditions
- Keep tightly sealed at room temperature (1-30 °C)
- Avoid direct sunlight, high temperature and humidity
Shelf Life
- Check the product packaging or labeling for the expiration date.
- Do not use if the product is expired.
Competitive Analysis & Comparison
เลื่อนตารางซ้าย ขวา เพื่อดูข้อมูลเพิ่มเติม
| Aspect | Matigen® | hADM (from human skin) | pADM (from porcine skin) |
|---|---|---|---|
| Biocompatibility | High biocompatibility with preserved extracellular matrix; designed to minimize immune response | Very high, closely resembles human tissue | Good, but slightly lower than human |
| Immune Risk | Very low; processed to remove cells, fats, viruses, and endotoxins. | Low (allograft) | Slightly higher (xenograft), but reduced with decellularization |
| Neovascularization / Integration | Rapid engraftment and stable integration; slower degradation than other ADMs | Excellent, new tissue integrates quickly | Good, though some studies report slower integration |
| Mechanical Strength | Available in multiple thicknesses (3–4 mm), maintains durability in collagenase test | Moderate to high, depending on model/thickness | Often slightly stronger, suitable for oral/nasal augmentation |
| Source / Sustainability | Manufactured from porcine dermis with standardized processing | Limited (requires human donation) | Abundant, easily reproducible |
| Cost | Moderately priced; generally lower than hADM but higher than basic pADM | Higher (due to scarcity and higher processing cost) | Lower / more accessible Retail price 600 – 800 THB/Unit |
| Patient Acceptance | Accepted in most regions; some cultural/religious restrictions due to porcine origin | Some patients may have ethical concerns about human use | Some patients (especially Muslim/Jewish) may refuse due to porcine origin |
| Typical Applications | Rhinoplasty (tip/saddle support), reconstructive surgery, soft-tissue augmentation | Breast reconstruction, burn surgery, rhinoplasty | Periodontal graft, dental implant soft-tissue augmentation |